Endocrine Abstracts

Introduction: Treatment using radioactive iodine (RAI) is used in several thyroid diseases, including differentiated thyroid carcinoma (DTC). The most frequent adverse effects include acute gastrointestinal symptoms, sialadenitis, xerostomia, cervical pain, and cervical swelling. Chronic symptoms such as obstruction of the salivary ducts, pulmonary fibrosis or other primary malignant diseases are also described. A single case of change in tongue pigmentation / lingua villosa n...

Paragangliomas (PGL) and pheochromocytomas (PHEO) are rare neuroendocrine tumors with an estimated prevalence of 1:6500 and 1:2500, respectively. Although most PGL/PHEO are benign, approximately 10% of PHEOs and 15-35% of PGLs have metastatic disease, which it is main cause of death, with 6 years of median survival. Objective: To characterize the metastatic PHEOs and PGLs from a single center. Methods: Retrospective analysis of clinical records of patients with metastatic PHEO...

Estrogen-producing adrenal gland tumors (EPAGT) are extremely rare, accounting for only 1–2% of all adrenal tumors. They are most commonly observed in men or in children, and are unusual in women. They are almost always malignant even if they seem benign at presentation, and most of them have a poor prognosis. We present a case of a 71-year-old man with painful bilateral gynecomastia, without galactorrhea, over 4 months. Markedly elevated plasma estradiol levels were foun...

Introduction: Primary hyperaldosteronism (PHA) and pheochromocytoma are endocrine causes of secondary arterial hypertension. The association of hyperaldosteronism and pheochromocytoma is rare and the involved mechanisms are poorly understood. Either there is coexistence of the two diseases (pheochromocytoma with PHA) or the pheochromocytoma stimulates the production of aldosterone.Case Report: Male, 54 years old, referred to our department for type 2 dia...

Introduction: About 5% of the adult population has adrenal incidentaloma(AI) and its incidence increases with age. AACE guidelines recommend image and hormonal evaluation during 5 years in non functioning AI. The european’s guidelines advise against repeat evaluation in non-secretory AI that present with <4 cm and had benign features. According to recent studies, the risk of developing clinically relevant hormone secretion is <0.3%, in patients with previous non-f...

Introduction: The quality of life (QoL) of patients with Diabetes has been the subject of several studies worldwide. In Portugal, studies have shown that patients under intensive insulin therapy had worse results in QoL questionnaires. The introduction of interstitial glucose monitoring (IGM) appears to reduce the impact of insulin therapy on QoL.Objective: To assess whether IGM changes the quality of life of patients with diabetes, compared to the asses...

Introduction: Diabetes is a disease with great psychosocial impact and reduced quality of life (QoL), and psychosocial factors seem to be excellent predictors of clinical outcomes.Objective: Assess the relationship between the patient’s perception of diabetes management and its impact on QoL.Methods: Interview of patients with type 1 (T1D) and type 2 diabetes (T2D), using the ‘Appraisal of Diabetes Scale’ (ADS), a qu...

Introduction: Obesity is a multifactorial and chronic disease. Bariatric surgery (BS) is the most effective treatment. A prevalence of 45% of esophagitis and 40%-70% of gastritis after BS has been reported. We analysed the presence of gastroesophageal lesions in patients who underwent BS (By-pass Roux-en-Y(BP) and gastric sleeve(GS)) in our centre.Methods: Patients submitted to BS between 2018-2020 were included. We retrospectively analysed clinical data...

Introduction: Thyroid nodules have a high prevalence in the adult population (20-76%). In 2018, the American College of Radiology proposed an ultrasound classification score of thyroid nodules - Thyroid Imaging Reporting and Data System-TIRADS, with 88% of sensitivity and 49% of specificity to predict malignancy. Since then, several studies report sensitivity values of 70.6-97% and specificity of 30-98%. We pretend to compared TIRADS score with cytologic results based on Bethe...

Introduction: Type 2 diabetes (T2D) is a heterogeneous disease for which causal mechanisms are incompletely understood and subclassification may improve patient management. In the latest assessment of patients with adult-onset diabetes, Ahlqvist and colleagues (2018) defined five new subgroups: an autoimmune form, two severe forms (insulin-deficient and insulin-resistant diabetes) and two mild forms (obesity and age-related diabetes).Objectives:...